MinDaP Research got Featured in Major News Medias
The recent research work based on a facile, cost-effective, disposable, and highly selective electrochemical immunosensing platform was featured in national major news medias. The work entitled "A Polyallylamine Anchored Amine-Rich Laser-Ablated Graphene Platform For Facile And Highly Selective Electrochemical IgG Biomarker Detection", has been recently published in a highly impacted international journal "Advanced Functional Materials". Here, for the first time, PAAMI is introduced to stabilize LAG flakes, while retaining the intrinsic thermal and electronic properties of the substrate by noncovalent π–π interaction and electrostatic physical absorption. The sensing platform offers a suitable number of anchoring sites for the immobi-lized antibodies by providing -NH2 functional groups. The proper grafting of PAAMI is confirmed through X-ray photoelectron spectroscopy and Raman spectroscopy. The immunosensing platform is applied to detect immuno-globulin (IgG) biomarkers as a proof of concept. Under optimized conditions, the sensing platform exhibits a linear range of 0.012–15 and 15–352 ng mL−1with a limit of detection of 6 pg mL−1 for IgG detection with high selectivity. Based on the analysis, the developed immunosensing platform can be used for point-of-care detection of IgG in clinical diagnostic centers. Furthermore, the developed strategy is well suited for the detection of other cancer bio-markers after immobilizing the relevant antibodies.
The research news is recently featured in national media Donga.
Read full news here Donga News.
